This course explores cutting-edge neurotechnology that is essential for advances in all aspects of neuroscience, including improvements in existing methods as well as the development, testing and discussion of completely new paradigms. Readings and in-class sessions cover the fields of electrophysiology, light microscopy, cellular engineering, optogenetics, electron microscopy, MRI / fMRI, and MEG / EEG.
This course develops and applies scaling laws and the methods of continuum and statistical mechanics to biomechanical phenomena over a range of length scales, from molecular to cellular to tissue or organ level.
With the growing availability and lowering costs of genotyping and personal genome sequencing, the focus has shifted from the ability to obtain the sequence to the ability to make sense of the resulting information. This course is aimed at exploring the computational challenges associated with interpreting how sequence differences between individuals lead to phenotypic differences in gene expression, disease predisposition, or response to treatment.
