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Video
Easy access to nutrients has contributed to the increase in obesity in the human population. But, what is obesity and why isn’t everybody fat? Dr. Stephen O’Rahilly provides a biomedical perspective of obesity, and evaluates which genes could potentially shift the balance towards obesity. As he explains, one becomes obese when the balance between energy intake and energy spent is shifted. Surprisingly, mutations that lead to obesity in humans aren’t in genes involved in metabolism and energy storage, but failure in satiety signals in the brain that result in people eating too much. The excess of energy intake over energy expenditure leads to obesity. What is the consequence of obesity in human health? Physically, obesity can result in lower mobility and sleeping disorders. But, in humans, the link between obesity and metabolic diseases isn’t straightforward. For example, not everyone that’s obese becomes insulin resistant. As O’Rahilly explains, the probability of an obese individual to have a metabolic disease is linked to the capacity of adipose tissue to store the extra fat. Mutations that decrease fat storage in adipose tissue increase the chance of metabolic diseases, like insulin resistance, even when the person is not obese.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Obesity -- Genetic aspects
- Resource Type:
- Video
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Video
Microglia are the primary immune cells in the central nervous system. In the brain, they play central roles in proper development and function, as well as dysfunction and disease. In her first talk, Dr. Beth Stevens provides an overview of the many ways microglia cells operate, and how they can both harm and protect the brain. Fairly recent advances in the study of microglia through imaging have allowed researchers to identify different microglia states and study their dynamic roles at different stages of development. In her second second talk, Dr. Stevens dives deeper into the mechanisms that allow microglia to shape the network of connections between neurons in the brain. She provides an introduction to the role of microglia in synaptic pruning, the process of eliminating extra synapses in healthy developing brains. She then goes on to explain how the reactivation of this process affects aging and diseased brains.
- Subjects:
- Medical Laboratory Science
- Keywords:
- Microglia Brain -- Diseases
- Resource Type:
- Video
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Video
Dr. Ernest Madu runs the Heart Institute of the Caribbean in Kingston, Jamaica, where he proves that -- with careful design, smart technical choices, and a true desire to serve -- it's possible to offer world-class healthcare in the developing world.
- Subjects:
- Management of Health Care Services and Health Sciences
- Keywords:
- Health services administration
- Resource Type:
- Video
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Video
Where you live: It impacts your health as much as diet and genes do, but it's not part of your medical records. At TEDMED, Bill Davenhall shows how overlooked government geo-data (from local heart-attack rates to toxic dumpsite info) can mesh with mobile GPS apps to keep doctors in the loop. Call it "geo-medicine."
- Subjects:
- Health Sciences
- Keywords:
- Medical geography
- Resource Type:
- Video
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Video
At TEDMED, Eric Dishman makes a bold argument: The US health care system is like computing circa 1959, tethered to big, unwieldy central systems: hospitals, doctors, nursing homes. As our aging population booms, it's imperative, he says, to create personal, networked, home-based health care for all.
- Subjects:
- Management of Health Care Services and Health Technology and Informatics
- Keywords:
- Health services administration Community health services Older people -- Medical care
- Resource Type:
- Video
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Video
Julian Treasure says our increasingly noisy world is gnawing away at our mental health -- even costing lives. He lays out an 8-step plan to soften this sonic assault (starting with those cheap earbuds) and restore our relationship with sound.
- Subjects:
- Health Sciences
- Keywords:
- Mental illness -- Prevention Noise pollution -- Health aspects
- Resource Type:
- Video
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Video
Surprising, but true: More women now die of heart disease than men, yet cardiovascular research has long focused on men. Pioneering doctor C. Noel Bairey Merz shares what we know and don't know about women's heart health -- including the remarkably different symptoms women present during a heart attack (and why they're often missed).
- Subjects:
- Health Sciences
- Keywords:
- Heart -- Diseases -- Research Heart diseases in women
- Resource Type:
- Video
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Video
Rebecca Onie asks audacious questions: What if waiting rooms were a place to improve daily health care? What if doctors could prescribe food, housing and heat in the winter? At TEDMED she describes Health Leads, an organization that does just that -- and does it by building a volunteer base as elite and dedicated as a college sports team.
- Subjects:
- Management of Health Care Services and Health Sciences
- Keywords:
- Social medicine Poor -- Medical care
- Resource Type:
- Video
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Video
Nearly 450 million people are affected by mental illness worldwide. In wealthy nations, just half receive appropriate care, but in developing countries, close to 90 percent go untreated because psychiatrists are in such short supply. Vikram Patel outlines a highly promising approach -- training members of communities to give mental health interventions, empowering ordinary people to care for others.
- Subjects:
- Health Sciences
- Keywords:
- Mental health service Mental health personnel -- Training of
- Resource Type:
- Video
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Video
Collecting global health data is an imperfect science: Workers tramp through villages to knock on doors and ask questions, write the answers on paper forms, then input the data -- and from this messy, gappy information, countries and NGOs need to make huge decisions. Data geek Joel Selanikio talks through the sea change in collecting health data in the past decade -- starting with the PalmPilot and Hotmail, and now moving into the cloud.
- Subjects:
- Health Technology and Informatics
- Keywords:
- Medicine -- Data processing Medical informatics
- Resource Type:
- Video