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  • Video 
    Pathology of Cardiac Disease (Screencast)

    Pathology of Cardiac Disease (Screencast)

    In this animated activity, learners examine the symptoms of four cardiac conditions: coronary artery disease, myocardial infarction, congestive heart failure, and valvular disease.

    Subjects:
    Health Sciences
    Keywords:
    Heart -- Diseases -- Diagnosis
    Resource Type:
    Video
     
  • Video 
    Major Muscles of the Human Body (Screencast)

    Major Muscles of the Human Body (Screencast)

    In this screencast, learners will match the muscle names to their corresponding locations in the human body.

    Subjects:
    Health Sciences, Rehabilation Sciences, and Biology
    Keywords:
    Human body Muscles
    Resource Type:
    Video
     
  • Video 
    Carbohydrate Digestion (Screencast)

    Carbohydrate Digestion (Screencast)

    In this screencast, learners examine the steps of carbohydrate digestion.

    Subjects:
    Health Sciences and Biology
    Keywords:
    Digestion Carbohydrates -- Metabolism
    Resource Type:
    Video
     
  • Video 
    Stages of Dental Plaque Formation (Screencast)

    Stages of Dental Plaque Formation (Screencast)

    In this screencast, students read about the stages of microbial dental plaque formation and the time it takes for each stage to occur.

    Subjects:
    Health Sciences
    Keywords:
    Teeth -- Diseases
    Resource Type:
    Video
     
  • Video 
    How the Brain Develops (Screencast)

    How the Brain Develops (Screencast)

    In this interactive learning object, learners study the parts of the brain and then test their knowledge in a drag-and-drop exercise.

    Subjects:
    Health Sciences and Human Biology
    Keywords:
    Brain -- Anatomy
    Resource Type:
    Video
     
  • Video 
    Arterial Blood Gas (Screencast)

    Arterial Blood Gas (Screencast)

    Students read an explanation of the values used for arterial blood gas analysis.

    Subjects:
    Health Sciences, Human Biology, and Medical Laboratory Science
    Keywords:
    Blood gases -- Measurement
    Resource Type:
    Video
     
  • Video 
    The Human Heart and the Cardiovascular System (Screencast)

    The Human Heart and the Cardiovascular System (Screencast)

    In this screencast, learners identify the parts of the cardiovascular system and examine blood flow.

    Subjects:
    Health Sciences and Human Biology
    Keywords:
    Heart Cardiovascular system
    Resource Type:
    Video
     
  • Video 
    The Electrocardiogram (Screencast)

    The Electrocardiogram (Screencast)

    In this animated object, learners view the "T" and "P" waves and the "QRS complex." A brief quiz completes the activity.

    Subjects:
    Health Sciences
    Keywords:
    Electrocardiography
    Resource Type:
    Video
     
  • Video 
    Nerve Action (Screencast)

    Nerve Action (Screencast)

    In this animated object, learners examine how the sensory, motor, mixed, and reflex nerves work in the human body.

    Subjects:
    Health Sciences and Human Biology
    Keywords:
    Neuroanatomy Perceptual-motor processes Reflexes
    Resource Type:
    Video
     
  • Video 
    Treatment of Tuberculosis, A Persistent Threat to Global Health

    Treatment of Tuberculosis, A Persistent Threat to Global Health

    Human population growth and urbanization have accelerated dramatically in recent centuries, providing unprecedented opportunities for microbes that use our bodies as vehicles for their own propagation and transmission. These conditions have led to the emergence of virulent new pathogens and the increased prevalence of “classic” scourges, such as Mycobacterium tuberculosis. This tenacious microbe is transmitted via infectious aerosols produced by individuals with pulmonary tuberculosis. Infection is lifelong and symptomatic tuberculosis may develop following a period of clinical latency lasting for months, years, or decades. The first part of this lecture provides an overview of the natural history of TB infection and the global impact of TB on human health. Tuberculosis remains one of the most important causes of human disease and death despite the introduction of vaccination in 1921 and chemotherapy in 1952. Although these interventions are inexpensive and widely available their impact is limited. The effectiveness of vaccination is unclear; in clinical trials, the protection conferred by vaccination has been variable and generally poor. Although chemotherapy can be highly effective, multiple drugs must be administered for 6-9 months to provide a reliable cure; the majority of tuberculosis patients are unable or unwilling to complete such a demanding regimen unless closely supervised. The second part of this lecture will discuss the challenges facing development of more effective vaccines and drugs for prevention and treatment of tuberculosis. The principal obstacle to successful treatment of tuberculosis is the lengthy duration of current regimens, which require administration of multiple drugs for 6-9 months. The requirement for prolonged therapy is attributed to sub-populations of bacillary “persisters” that are refractory to antimicrobials. The persisters are not drug-resistant in the conventional (heritable) sense and it is a mystery why they are spared whilst their genetically identical siblings are killed. The third part of this lecture describes recent work in our laboratory using microfluidics and time-lapse microscopy to analyze the behavior of drug-stressed bacteria at single-cell resolution. These studies challenge conventional views of how antimicrobials kill (or fail to kill) bacteria. All pathogens must acquire and assimilate nutrients from their hosts in order to grow and multiply — our tissues are literally their food — yet surprisingly little is known about this fundamental aspect of the pathogenic lifestyle. Accumulating evidence suggests that M. tuberculosis might utilize fatty acids as its principal carbon and energy source during infection. The fourth part of this lecture describes work in our laboratory that is focused on identifying the metabolic pathways that are essential for growth and persistence of M. tuberculosis in vivo. Some of these pathways are potentially interesting targets for antimicrobial drug development, as they are not found in human cells.

    Subjects:
    Public Health and Health Sciecnes
    Keywords:
    Tuberculosis Public health
    Resource Type:
    Video