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The aim of this class is to introduce the exciting and often under appreciated discoveries in RNA biology by exploring the diversity of RNAs—encompassing classical molecules such as ribosomal RNAs (rRNAs), transfer RNAs (tRNAs) and messenger RNAs (mRNAs) as well as newer species, such as microRNAs (miRNAs), long-noncoding RNAs (lncRNAs), and circular RNAs (circRNAs). For each new class of RNA, we will evaluate the evidence for its existence as well as for its proposed function. Students will develop both a deep understanding of the field of RNA biology and the ability to critically assess new papers in this fast-paced field. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
- Subjects:
- Biology
- Keywords:
- RNA
- Resource Type:
- Courseware
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Courseware
This course is intended for the student interested in understanding and appreciating common biological topics in the study of the smallest units within biology: molecules and cells. Molecular and cellular biology is a dynamic field. There are thousands of opportunities within the medical, pharmaceutical, agricultural, and industrial fields (just to name a few) for a person with a concentrated knowledge of molecular and cellular processes. This course will give you a general introduction to these topics. In addition to preparing for a diversity of career paths, an understanding of molecular and cell biology will help you make sound decisions in your everyday life that can positively impact your diet and health. This course includes the following units: Unit 1: Introduction to Biology Unit 2: Basic Chemistry Unit 3: Biological Molecules Unit 4: Cells and Cell Membranes Unit 5: Enzymes, Metabolism, Cellular Respiration Unit 6: Photosynthesis Unit 7: Cellular Reproduction: Mitosis Unit 8: Cellular Reproduction: Meiosis Unit 9: Mendelian Genetics and Chromosomes Unit 10: Gene Expression
- Course related:
- ABCT1102 General Biology and ABCT2312 Introductory Cell Biology and Biochemistry
- Subjects:
- Biology
- Keywords:
- Cytology Molecular biology
- Resource Type:
- Courseware
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Courseware
Cell biology, biochemistry, genetics, and the biology of organ systems, Covers concepts of building blocks (nucleotides, amino acids, and cells) and of information flow (DNA to proteins, receptors to nuclei, the blood to distant organs, and DNA to offspring)
- Subjects:
- Biology
- Keywords:
- DNA Biochemistry Cytology Biology
- Resource Type:
- Courseware
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Courseware
Patterns of diversity, ecology, and evolutionary biology. Emphasis is on the Tree of Life and how its members are distributed and interact. Partial Course.
- Subjects:
- Biology
- Keywords:
- Biodiversity Ecology Evolution (Biology)
- Resource Type:
- Courseware
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Courseware
Antibodies, antigens, antigen-antibody reactions, cells and tissues of lymphoreticular and hematopoietic systems, and individual and collective components of cell-mediated and humoral immune response,
- Subjects:
- Biology
- Keywords:
- Hematology Immunology
- Resource Type:
- Courseware
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Courseware
This course is an advanced treatment of biochemical mechanisms that underlie biological processes. Topics include macromolecular machines such as the ribosome, the proteasome, fatty acid synthases as a paradigm for polyketide synthases and non-ribosomal polypeptide synthases, and polymerases. Emphasis will be given to the experimental methods used to unravel how these processes fit into the cellular context as well as the coordinated regulation of these processes.
- Subjects:
- Biochemistry and Biology
- Keywords:
- Biochemistry
- Resource Type:
- Courseware
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Courseware
Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
- Subjects:
- Chemistry and Biology
- Keywords:
- Chemistry Organic Biochemistry
- Resource Type:
- Courseware
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Courseware
With the growing availability and lowering costs of genotyping and personal genome sequencing, the focus has shifted from the ability to obtain the sequence to the ability to make sense of the resulting information. This course is aimed at exploring the computational challenges associated with interpreting how sequence differences between individuals lead to phenotypic differences in gene expression, disease predisposition, or response to treatment.
- Subjects:
- Computing and Biology
- Keywords:
- Genomics Genomes
- Resource Type:
- Courseware
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Courseware
On the 28th of April 2012 the contents of the English as well as German Wikibooks and Wikipedia projects were licensed under Creative Commons Attribution-ShareAlike 3.0 Unported license. An URI to this license is given in the list of figures on page 175. If this document is a derived work from the contents of one of these projects and the content was still licensed by the project under this license at the time of derivation this document has to be licensed under the same, a similar or a compatible license, as stated in section 4b of the license. The list of contributors is included in chapter Contributors on page 169. The licenses GPL, LGPL and GFDL are included in chapter Licenses on page 179, since this book and/or parts of it may or may not be licensed under one or more of these licenses, and thus require inclusion of these licenses. The licenses of the figures are given in the list of figures on page 175. This PDF was generated by the LATEX typesetting software. The LATEX source code is included as an attachment (source.7z.txt) in this PDF file. To extract the source from the PDF file, we recommend the use of http://www.pdflabs.com/tools/pdftk-the-pdf-toolkit/ utility or clicking the paper clip attachment symbol on the lower left of your PDF Viewer, selecting Save Attachment. After extracting it from the PDF file you have to rename it to source.7z. To uncompress the resulting archive we recommend the use of http://www.7-zip.org/. The LATEX source itself was generated by a program written by Dirk Hünniger, which is freely available under an open source license from http://de.wikibooks.org/wiki/Benutzer:Dirk_Huenniger/wb2pdf. This distribution also contains a configured version of the pdflatex compiler with all necessary packages and fonts needed to compile the LATEX source included in this PDF file.
- Subjects:
- Biology
- Keywords:
- Biology
- Resource Type:
- Courseware
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Courseware
Parasites require a hospitable organism to reproduce and spread and have evolved multiple strategies to subvert their hosts. Parasites scavenge nutrients directly from host cells, evade the host immune system and even modify host behavior to increase their transmission. This course will explore the strategies used by a ubiquitous and harmful class of parasites to hijack the biology of their host cells. We will discuss pathogens such as Plasmodium and Toxoplasma, responsible for some of the deadliest and most pervasive infectious diseases on the planet. By exploring how these pathogens invade a host cell and replicate while evading the immune system, students will gain a broad understanding of basic cell biology, biochemistry and immunology, as well as learn techniques commonly used in cell biology. Students will be challenged to think creatively and flexibly to understand, critique, interpret, and design scientific experiments in the field of host-pathogen interactions.
- Subjects:
- Biology
- Keywords:
- Pathogenic microorganisms Parasites
- Resource Type:
- Courseware