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In this interactive object, learners examine the structure and function of the sense of taste.
- Subjects:
- Health Sciences and Human Biology
- Keywords:
- Taste
- Resource Type:
- Others
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Others
In this animated and interactive object, learners examine ABO blood antigens and Rh antigens and their compatibility.
- Subjects:
- Health Sciences, Human Biology, and Medical Laboratory Science
- Keywords:
- Bood groups
- Resource Type:
- Others
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Video
Human population growth and urbanization have accelerated dramatically in recent centuries, providing unprecedented opportunities for microbes that use our bodies as vehicles for their own propagation and transmission. These conditions have led to the emergence of virulent new pathogens and the increased prevalence of “classic” scourges, such as Mycobacterium tuberculosis. This tenacious microbe is transmitted via infectious aerosols produced by individuals with pulmonary tuberculosis. Infection is lifelong and symptomatic tuberculosis may develop following a period of clinical latency lasting for months, years, or decades. The first part of this lecture provides an overview of the natural history of TB infection and the global impact of TB on human health. Tuberculosis remains one of the most important causes of human disease and death despite the introduction of vaccination in 1921 and chemotherapy in 1952. Although these interventions are inexpensive and widely available their impact is limited. The effectiveness of vaccination is unclear; in clinical trials, the protection conferred by vaccination has been variable and generally poor. Although chemotherapy can be highly effective, multiple drugs must be administered for 6-9 months to provide a reliable cure; the majority of tuberculosis patients are unable or unwilling to complete such a demanding regimen unless closely supervised. The second part of this lecture will discuss the challenges facing development of more effective vaccines and drugs for prevention and treatment of tuberculosis. The principal obstacle to successful treatment of tuberculosis is the lengthy duration of current regimens, which require administration of multiple drugs for 6-9 months. The requirement for prolonged therapy is attributed to sub-populations of bacillary “persisters” that are refractory to antimicrobials. The persisters are not drug-resistant in the conventional (heritable) sense and it is a mystery why they are spared whilst their genetically identical siblings are killed. The third part of this lecture describes recent work in our laboratory using microfluidics and time-lapse microscopy to analyze the behavior of drug-stressed bacteria at single-cell resolution. These studies challenge conventional views of how antimicrobials kill (or fail to kill) bacteria. All pathogens must acquire and assimilate nutrients from their hosts in order to grow and multiply — our tissues are literally their food — yet surprisingly little is known about this fundamental aspect of the pathogenic lifestyle. Accumulating evidence suggests that M. tuberculosis might utilize fatty acids as its principal carbon and energy source during infection. The fourth part of this lecture describes work in our laboratory that is focused on identifying the metabolic pathways that are essential for growth and persistence of M. tuberculosis in vivo. Some of these pathways are potentially interesting targets for antimicrobial drug development, as they are not found in human cells.
- Subjects:
- Public Health and Health Sciecnes
- Keywords:
- Tuberculosis Public health
- Resource Type:
- Video
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Video
Listen closely -- Marvin Minsky's arch, eclectic, charmingly offhand talk on health, overpopulation and the human mind is packed with subtlety: wit, wisdom and just an ounce of wily, is-he-joking? advice.
- Subjects:
- Social Sciences
- Keywords:
- Overpopulation Social problems
- Resource Type:
- Video
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Video
For a full year, A.J. Jacobs followed every piece of health advice he could -- from applying sunscreen by the shot glass to wearing a bicycle helmet while shopping. Onstage at TEDMED, he shares the surprising things he learned.
- Subjects:
- Health Sciences
- Keywords:
- Health behavior Noise pollution Joy
- Resource Type:
- Video
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Video
You can use your smartphone to find a local ATM, but what if you need a defibrillator? Lucien Engelen shows us online innovations that are changing the way we save lives, including a crowdsourced map of local AEDs.
- Subjects:
- Health Sciences and Health Technology and Informatics
- Keywords:
- Medical care Medical technology
- Resource Type:
- Video
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Video
Bees have been rapidly and mysteriously disappearing from rural areas, with grave implications for agriculture. But bees seem to flourish in urban environments -- and cities need their help, too. Noah Wilson-Rich suggests that urban beekeeping might play a role in revitalizing both a city and a species.
- Subjects:
- Environmental Sciences and Biology
- Keywords:
- Honeybees
- Resource Type:
- Video
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Video
Adam Garone has an impressive moustache, and it's for a good cause. A co-founder of Movember, Garone's initiative to raise awareness for men's health -- by having men grow out their moustaches every November -- began as a dare in a bar in 2003. Now, it's a worldwide movement that raised $126 million for prostate cancer research last year.
- Subjects:
- Health Sciences
- Keywords:
- Health promotion Fund raising Prostate -- Cancer
- Resource Type:
- Video
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Video
How do cancer cells grow? How does chemotherapy fight cancer (and cause negative side effects)? The answers lie in cell division. George Zaidan explains how rapid cell division is cancer's "strength" -- and also its weakness.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Cancer cells
- Resource Type:
- Video
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Video
When Eric Dishman was in college, doctors told him he had 2 to 3 years to live. That was a long time ago. Now, Dishman puts his experience and his expertise as a medical tech specialist together to suggest a bold idea for reinventing health care -- by putting the patient at the center of a treatment team.
- Subjects:
- Management of Health Care Services
- Keywords:
- Medical care Health services administration
- Resource Type:
- Video