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Sue Desmond-Hellmann is using precision public health -- an approach that incorporates big data, consumer monitoring, gene sequencing and other innovative tools -- to solve the world's most difficult medical problems. It's already helped cut HIV transmission from mothers to babies by nearly half in sub-Saharan Africa, and now it's being used to address alarming infant mortality rates all over the world. The goal: to save lives by bringing the right interventions to the right populations at the right time.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Medicial informatics Big data Public health
- Resource Type:
- Video
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Video
Can we make tattoos both beautiful and functional? Nanotechnologist Carson Bruns shares his work creating high-tech tattoos that react to their environment -- like color-changing ink that can tell you when you're getting a sunburn -- and shows exciting ways they can deliver real-time information about our health.
- Subjects:
- Health Technology and Informatics and Biology
- Keywords:
- Tattooing -- Health aspects
- Resource Type:
- Video
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Video
Your lifelong health may have been decided the day you were born, says microbiome researcher Henna-Maria Uusitupa. In this fascinating talk, she shows how the gut microbes you acquire during birth and as an infant impact your health into adulthood -- and discusses new microbiome research that could help tackle problems like obesity and diabetes.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Microorganisms Medical genetics
- Resource Type:
- Video
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Video
Easy access to nutrients has contributed to the increase in obesity in the human population. But, what is obesity and why isn’t everybody fat? Dr. Stephen O’Rahilly provides a biomedical perspective of obesity, and evaluates which genes could potentially shift the balance towards obesity. As he explains, one becomes obese when the balance between energy intake and energy spent is shifted. Surprisingly, mutations that lead to obesity in humans aren’t in genes involved in metabolism and energy storage, but failure in satiety signals in the brain that result in people eating too much. The excess of energy intake over energy expenditure leads to obesity. What is the consequence of obesity in human health? Physically, obesity can result in lower mobility and sleeping disorders. But, in humans, the link between obesity and metabolic diseases isn’t straightforward. For example, not everyone that’s obese becomes insulin resistant. As O’Rahilly explains, the probability of an obese individual to have a metabolic disease is linked to the capacity of adipose tissue to store the extra fat. Mutations that decrease fat storage in adipose tissue increase the chance of metabolic diseases, like insulin resistance, even when the person is not obese.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Obesity -- Genetic aspects
- Resource Type:
- Video