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Video
How do cancer cells grow? How does chemotherapy fight cancer (and cause negative side effects)? The answers lie in cell division. George Zaidan explains how rapid cell division is cancer's "strength" -- and also its weakness.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Cancer cells
- Resource Type:
- Video
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Video
Masterpieces of microengineering, kinesins are motorized transport machines that move cellular materials to their correct locations in the cell so they can perform their functions. Kinesins have two feet, or "globular heads," that literally walk, one foot over another. Known as the "workhorses of the cell," kinesins can carry cargo many times their own size.
- Course related:
- ABCT2103 Cell Biology
- Subjects:
- Biology
- Keywords:
- Kinesin
- Resource Type:
- Video
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Courseware
This course is intended for the student interested in understanding and appreciating common biological topics in the study of the smallest units within biology: molecules and cells. Molecular and cellular biology is a dynamic field. There are thousands of opportunities within the medical, pharmaceutical, agricultural, and industrial fields (just to name a few) for a person with a concentrated knowledge of molecular and cellular processes. This course will give you a general introduction to these topics. In addition to preparing for a diversity of career paths, an understanding of molecular and cell biology will help you make sound decisions in your everyday life that can positively impact your diet and health. This course includes the following units: Unit 1: Introduction to Biology Unit 2: Basic Chemistry Unit 3: Biological Molecules Unit 4: Cells and Cell Membranes Unit 5: Enzymes, Metabolism, Cellular Respiration Unit 6: Photosynthesis Unit 7: Cellular Reproduction: Mitosis Unit 8: Cellular Reproduction: Meiosis Unit 9: Mendelian Genetics and Chromosomes Unit 10: Gene Expression
- Course related:
- ABCT1102 General Biology and ABCT2312 Introductory Cell Biology and Biochemistry
- Subjects:
- Biology
- Keywords:
- Cytology Molecular biology
- Resource Type:
- Courseware
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e-book
A grasp of the logic and practice of science is essential to understand the rest of the world around us. To that end, the CMB3e iText (like earlier editions) remains focused on experimental support for what we know about cell and molecular biology, and on showing students the relationship of cell structure and function. Rather than trying to be a comprehensive reference book, CMB3e selectively details investigative questions, methods and experiments that lead to our understanding of cell biology. This focus is nowhere more obvious than in the chapter learning objectives and in external links to supplementary material. The Basic CMB3e version of the iText includes links to external web-sources as well as the author’s short, just-in-time YouTube VOPs (with edited, optional closed captions), all embedded in or near relevant text. Each video is identified with a descriptive title and video play and QR bar codes. The Learning objectives align with content and ask students to use new knowledge to make connections and deepen their understanding of concept and experiment. All external links are intended to expand or explain textual content and concepts and to engage student curiosity. Links to full VOP lectures are now at the back of the book. include optional edited closed captions. All images in the iText are by the author or are from public domain or Creative Commons (CC) licensed sources. For all externally sourced images, CC licenses are indicated with the image. Beyond the Basic CMB3e, the freely available Annotated CMB3e contains interactive links and formative assessments in the form of Challenge boxes. A CMB3e Sample Chapter and CMB3e iText for Instructors model additional interactive features, including short 25 Words or Less writing assignments that can be incorporated into almost any course management system, and all of which the author assigned as homework in his flipped, blended course. These assessments aim to reinforce writing as well as critical thinking skills. The CMB3e Sample Chapter is freely available for download; the CMB3e for Instructors version of the iText is available on request. My goal in writing this iText is to make the content engaging, free and comparable in accuracy and currency to commercial textbooks. I encourage instructors to use the interactive features of the iText (critical thought questions, YouTube videos, etc.) to challenge their students. With all of these enhancements, I encourage students to think about • how good and great experiments were inspired and designed, • how alternative experimental results were predicted, • how data was interpreted, and finally, • investigators (and we!) arrive at the most interesting “next questions”. The online iText is the most efficient way to access links and complete online assignments. Nevertheless, you can download, read, study, and access many links with a smart phone or tablet. And you can add your own annotations digitally, or write in the margins of a printout the old-fashioned way! Your instructor may provide additional instructions for using your iText.
- Subjects:
- Biology
- Keywords:
- Textbooks Cytology Molecular biology
- Resource Type:
- e-book
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Courseware
This course is an advanced treatment of biochemical mechanisms that underlie biological processes. Topics include macromolecular machines such as the ribosome, the proteasome, fatty acid synthases as a paradigm for polyketide synthases and non-ribosomal polypeptide synthases, and polymerases. Emphasis will be given to the experimental methods used to unravel how these processes fit into the cellular context as well as the coordinated regulation of these processes.
- Subjects:
- Biochemistry and Biology
- Keywords:
- Biochemistry
- Resource Type:
- Courseware
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Courseware
The aim of this class is to introduce the exciting and often under appreciated discoveries in RNA biology by exploring the diversity of RNAs—encompassing classical molecules such as ribosomal RNAs (rRNAs), transfer RNAs (tRNAs) and messenger RNAs (mRNAs) as well as newer species, such as microRNAs (miRNAs), long-noncoding RNAs (lncRNAs), and circular RNAs (circRNAs). For each new class of RNA, we will evaluate the evidence for its existence as well as for its proposed function. Students will develop both a deep understanding of the field of RNA biology and the ability to critically assess new papers in this fast-paced field. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
- Subjects:
- Biology
- Keywords:
- RNA
- Resource Type:
- Courseware
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Courseware
In this course, we will investigate the diverse types and functions of different RNA species, with a focus on "non-coding RNAs," i.e. those that do not directly encode proteins. The course will convey both the exciting discoveries in and frontiers of RNA research that are propelling our understanding of cell biology as well as the intellectual and experimental approaches responsible. The molecular biology revolution firmly established the role of DNA as the primary carrier of genetic information and proteins as the primary effector molecules of the cell. The intermediate between DNA and proteins is RNA, which initially was regarded as the "molecule in the middle" of the central dogma. This view has been transformed over the past two decades, as RNA has become recognized as a critical regulator of cellular processes.
- Subjects:
- Biology
- Keywords:
- Non-coding RNA RNA
- Resource Type:
- Courseware