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Courseware
This course is intended for the student interested in understanding and appreciating common biological topics in the study of the smallest units within biology: molecules and cells. Molecular and cellular biology is a dynamic field. There are thousands of opportunities within the medical, pharmaceutical, agricultural, and industrial fields (just to name a few) for a person with a concentrated knowledge of molecular and cellular processes. This course will give you a general introduction to these topics. In addition to preparing for a diversity of career paths, an understanding of molecular and cell biology will help you make sound decisions in your everyday life that can positively impact your diet and health. This course includes the following units: Unit 1: Introduction to Biology Unit 2: Basic Chemistry Unit 3: Biological Molecules Unit 4: Cells and Cell Membranes Unit 5: Enzymes, Metabolism, Cellular Respiration Unit 6: Photosynthesis Unit 7: Cellular Reproduction: Mitosis Unit 8: Cellular Reproduction: Meiosis Unit 9: Mendelian Genetics and Chromosomes Unit 10: Gene Expression
- Course related:
- ABCT1102 General Biology and ABCT2312 Introductory Cell Biology and Biochemistry
- Subjects:
- Biology
- Keywords:
- Cytology Molecular biology
- Resource Type:
- Courseware
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Courseware
On the 28th of April 2012 the contents of the English as well as German Wikibooks and Wikipedia projects were licensed under Creative Commons Attribution-ShareAlike 3.0 Unported license. An URI to this license is given in the list of figures on page 175. If this document is a derived work from the contents of one of these projects and the content was still licensed by the project under this license at the time of derivation this document has to be licensed under the same, a similar or a compatible license, as stated in section 4b of the license. The list of contributors is included in chapter Contributors on page 169. The licenses GPL, LGPL and GFDL are included in chapter Licenses on page 179, since this book and/or parts of it may or may not be licensed under one or more of these licenses, and thus require inclusion of these licenses. The licenses of the figures are given in the list of figures on page 175. This PDF was generated by the LATEX typesetting software. The LATEX source code is included as an attachment (source.7z.txt) in this PDF file. To extract the source from the PDF file, we recommend the use of http://www.pdflabs.com/tools/pdftk-the-pdf-toolkit/ utility or clicking the paper clip attachment symbol on the lower left of your PDF Viewer, selecting Save Attachment. After extracting it from the PDF file you have to rename it to source.7z. To uncompress the resulting archive we recommend the use of http://www.7-zip.org/. The LATEX source itself was generated by a program written by Dirk Hünniger, which is freely available under an open source license from http://de.wikibooks.org/wiki/Benutzer:Dirk_Huenniger/wb2pdf. This distribution also contains a configured version of the pdflatex compiler with all necessary packages and fonts needed to compile the LATEX source included in this PDF file.
- Subjects:
- Biology
- Keywords:
- Biology
- Resource Type:
- Courseware
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Courseware
This course is an advanced treatment of biochemical mechanisms that underlie biological processes. Topics include macromolecular machines such as the ribosome, the proteasome, fatty acid synthases as a paradigm for polyketide synthases and non-ribosomal polypeptide synthases, and polymerases. Emphasis will be given to the experimental methods used to unravel how these processes fit into the cellular context as well as the coordinated regulation of these processes.
- Subjects:
- Biochemistry and Biology
- Keywords:
- Biochemistry
- Resource Type:
- Courseware
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Courseware
The MIT Biology Department core Introductory Biology courses, 7.012, 7.013, 7.014, 7.015, and 7.016 all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. The focus of 7.013 is on genomic approaches to human biology, including neuroscience, development, immunology, tissue repair and stem cells, tissue engineering, and infectious and inherited diseases, including cancer.
- Subjects:
- Biology
- Keywords:
- Human biology Biology
- Resource Type:
- Courseware
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Courseware
This course explores cutting-edge neurotechnology that is essential for advances in all aspects of neuroscience, including improvements in existing methods as well as the development, testing and discussion of completely new paradigms. Readings and in-class sessions cover the fields of electrophysiology, light microscopy, cellular engineering, optogenetics, electron microscopy, MRI / fMRI, and MEG / EEG.
- Subjects:
- Biomedical Engineering and Biology
- Keywords:
- Neurotechnology (Bioengineering)
- Resource Type:
- Courseware
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Courseware
This course develops and applies scaling laws and the methods of continuum and statistical mechanics to biomechanical phenomena over a range of length scales, from molecular to cellular to tissue or organ level.
- Subjects:
- Biomedical Engineering and Biology
- Keywords:
- Biomedical engineering Biomechanics
- Resource Type:
- Courseware
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Courseware
This course is intended for both mathematics and biology undergrads with a basic mathematics background, and consists of an introduction to modeling biological problems using continuous ODE methods (rather than discrete methods as used in 113A). We describe the basic qualitative behavior of dynamical systems in the context of a simple population model and, as time allows, introduce other types of models such as chemical reactions inside the cell or excitable systems leading to oscillations and neuronal signals. Certain topics from linear algebra that are needed for this course are presented as well, so a linear algebra prerequisite is not necessary.
- Subjects:
- Mathematics and Statistics and Biology
- Keywords:
- Biology -- Mathematical models
- Resource Type:
- Courseware
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Courseware
Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
- Subjects:
- Chemistry and Biology
- Keywords:
- Chemistry Organic Biochemistry
- Resource Type:
- Courseware
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Courseware
Antibodies, antigens, antigen-antibody reactions, cells and tissues of lymphoreticular and hematopoietic systems, and individual and collective components of cell-mediated and humoral immune response,
- Subjects:
- Biology
- Keywords:
- Hematology Immunology
- Resource Type:
- Courseware
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Courseware
Cell biology, biochemistry, genetics, and the biology of organ systems, Covers concepts of building blocks (nucleotides, amino acids, and cells) and of information flow (DNA to proteins, receptors to nuclei, the blood to distant organs, and DNA to offspring)
- Subjects:
- Biology
- Keywords:
- DNA Biochemistry Cytology Biology
- Resource Type:
- Courseware
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Courseware
Patterns of diversity, ecology, and evolutionary biology. Emphasis is on the Tree of Life and how its members are distributed and interact. Partial Course.
- Subjects:
- Biology
- Keywords:
- Biodiversity Ecology Evolution (Biology)
- Resource Type:
- Courseware
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Courseware
Provides students with the basic tools for analyzing experimental data, properly interpreting statistical reports in the literature, and reasoning under uncertain situations. Topics organized around three key theories: Probability, statistical, and the linear model. Probability theory covers axioms of probability, discrete and continuous probability models, law of large numbers, and the Central Limit Theorem. Statistical theory covers estimation, likelihood theory, Bayesian methods, bootstrap and other Monte Carlo methods, as well as hypothesis testing, confidence intervals, elementary design of experiments principles and goodness-of-fit. The linear model theory covers the simple regression model and the analysis of variance. Places equal emphasis on theory, data analyses, and simulation studies.
- Subjects:
- Mathematics and Statistics and Biology
- Keywords:
- Statistics Cognitive science
- Resource Type:
- Courseware
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Courseware
With the growing availability and lowering costs of genotyping and personal genome sequencing, the focus has shifted from the ability to obtain the sequence to the ability to make sense of the resulting information. This course is aimed at exploring the computational challenges associated with interpreting how sequence differences between individuals lead to phenotypic differences in gene expression, disease predisposition, or response to treatment.
- Subjects:
- Computing and Biology
- Keywords:
- Genomics Genomes
- Resource Type:
- Courseware
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Courseware
The aim of this class is to introduce the exciting and often under appreciated discoveries in RNA biology by exploring the diversity of RNAs—encompassing classical molecules such as ribosomal RNAs (rRNAs), transfer RNAs (tRNAs) and messenger RNAs (mRNAs) as well as newer species, such as microRNAs (miRNAs), long-noncoding RNAs (lncRNAs), and circular RNAs (circRNAs). For each new class of RNA, we will evaluate the evidence for its existence as well as for its proposed function. Students will develop both a deep understanding of the field of RNA biology and the ability to critically assess new papers in this fast-paced field. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
- Subjects:
- Biology
- Keywords:
- RNA
- Resource Type:
- Courseware
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Courseware
In this course, we will investigate the diverse types and functions of different RNA species, with a focus on "non-coding RNAs," i.e. those that do not directly encode proteins. The course will convey both the exciting discoveries in and frontiers of RNA research that are propelling our understanding of cell biology as well as the intellectual and experimental approaches responsible. The molecular biology revolution firmly established the role of DNA as the primary carrier of genetic information and proteins as the primary effector molecules of the cell. The intermediate between DNA and proteins is RNA, which initially was regarded as the "molecule in the middle" of the central dogma. This view has been transformed over the past two decades, as RNA has become recognized as a critical regulator of cellular processes.
- Subjects:
- Biology
- Keywords:
- Non-coding RNA RNA
- Resource Type:
- Courseware
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Courseware
How do we sense hunger? How do we sense pain? What causes growth in our bodies? How are we protected from pathogens? The answer to many of these questions involves small polymers of amino acids known as peptides. Peptides are broadly used as signal molecules for intercellular communication in prokaryotes, plants, fungi, and animals. Peptide signals in animals include vast numbers of peptide hormones, growth factors and neuropeptides. In this course, we will learn about molecular bases of peptide signaling. In addition, peptides potentially can be used as potent broad-spectrum antibiotics and hence might define novel therapeutic agents.
- Subjects:
- Biology
- Keywords:
- Peptides
- Resource Type:
- Courseware
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Courseware
Parasites require a hospitable organism to reproduce and spread and have evolved multiple strategies to subvert their hosts. Parasites scavenge nutrients directly from host cells, evade the host immune system and even modify host behavior to increase their transmission. This course will explore the strategies used by a ubiquitous and harmful class of parasites to hijack the biology of their host cells. We will discuss pathogens such as Plasmodium and Toxoplasma, responsible for some of the deadliest and most pervasive infectious diseases on the planet. By exploring how these pathogens invade a host cell and replicate while evading the immune system, students will gain a broad understanding of basic cell biology, biochemistry and immunology, as well as learn techniques commonly used in cell biology. Students will be challenged to think creatively and flexibly to understand, critique, interpret, and design scientific experiments in the field of host-pathogen interactions.
- Subjects:
- Biology
- Keywords:
- Pathogenic microorganisms Parasites
- Resource Type:
- Courseware