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When stress got to be too much for TED Fellow Sangu Delle, he had to confront his own deep prejudice: that men shouldn't take care of their mental health. In a personal talk, Delle shares how he learned to handle anxiety in a society that's uncomfortable with emotions. As he says: "Being honest about how we feel doesn't make us weak -- it makes us human."
- Subjects:
- Health Sciences
- Keywords:
- Mental health
- Resource Type:
- Video
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Video
Human population growth and urbanization have accelerated dramatically in recent centuries, providing unprecedented opportunities for microbes that use our bodies as vehicles for their own propagation and transmission. These conditions have led to the emergence of virulent new pathogens and the increased prevalence of “classic” scourges, such as Mycobacterium tuberculosis. This tenacious microbe is transmitted via infectious aerosols produced by individuals with pulmonary tuberculosis. Infection is lifelong and symptomatic tuberculosis may develop following a period of clinical latency lasting for months, years, or decades. The first part of this lecture provides an overview of the natural history of TB infection and the global impact of TB on human health. Tuberculosis remains one of the most important causes of human disease and death despite the introduction of vaccination in 1921 and chemotherapy in 1952. Although these interventions are inexpensive and widely available their impact is limited. The effectiveness of vaccination is unclear; in clinical trials, the protection conferred by vaccination has been variable and generally poor. Although chemotherapy can be highly effective, multiple drugs must be administered for 6-9 months to provide a reliable cure; the majority of tuberculosis patients are unable or unwilling to complete such a demanding regimen unless closely supervised. The second part of this lecture will discuss the challenges facing development of more effective vaccines and drugs for prevention and treatment of tuberculosis. The principal obstacle to successful treatment of tuberculosis is the lengthy duration of current regimens, which require administration of multiple drugs for 6-9 months. The requirement for prolonged therapy is attributed to sub-populations of bacillary “persisters” that are refractory to antimicrobials. The persisters are not drug-resistant in the conventional (heritable) sense and it is a mystery why they are spared whilst their genetically identical siblings are killed. The third part of this lecture describes recent work in our laboratory using microfluidics and time-lapse microscopy to analyze the behavior of drug-stressed bacteria at single-cell resolution. These studies challenge conventional views of how antimicrobials kill (or fail to kill) bacteria. All pathogens must acquire and assimilate nutrients from their hosts in order to grow and multiply — our tissues are literally their food — yet surprisingly little is known about this fundamental aspect of the pathogenic lifestyle. Accumulating evidence suggests that M. tuberculosis might utilize fatty acids as its principal carbon and energy source during infection. The fourth part of this lecture describes work in our laboratory that is focused on identifying the metabolic pathways that are essential for growth and persistence of M. tuberculosis in vivo. Some of these pathways are potentially interesting targets for antimicrobial drug development, as they are not found in human cells.
- Subjects:
- Public Health and Health Sciecnes
- Keywords:
- Tuberculosis Public health
- Resource Type:
- Video
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Video
We may not be as deeply divided as we think -- at least when it comes to health, says Rebecca Onie. In a talk that cuts through the noise, Onie shares research that shows how, even across economic, political and racial divides, Americans agree on what they need to live good lives -- and asks both health care providers and patients to focus on what makes us healthy, not what makes us angry.
- Subjects:
- Public Heath and Management of Health Care Services
- Keywords:
- Medical care Social medicine
- Resource Type:
- Video
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Video
In the US, the very same blood test can cost $19 at one clinic and $522 at another clinic just blocks away -- and nobody knows the difference until they get a bill weeks later. Journalist Jeanne Pinder says it doesn't have to be this way. She's built a platform that crowdsources the true costs of medical procedures and makes the data public, revealing the secrets of health care pricing. Learn how knowing what stuff costs in advance could make us healthier, save us money -- and help fix a broken system.
- Subjects:
- Management of Health Care Services and Health Sciences
- Keywords:
- Medical care -- Cost control Medical care Cost of
- Resource Type:
- Video
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Video
Rebecca Onie asks audacious questions: What if waiting rooms were a place to improve daily health care? What if doctors could prescribe food, housing and heat in the winter? At TEDMED she describes Health Leads, an organization that does just that -- and does it by building a volunteer base as elite and dedicated as a college sports team.
- Subjects:
- Management of Health Care Services and Health Sciences
- Keywords:
- Social medicine Poor -- Medical care
- Resource Type:
- Video
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Video
Raj Panjabi's life work has been to support and employ community health workers in the country of Liberia, where he grew up. In this talk, the TED Prize winner expands his vision. Over the next three years, his nonprofit Last Mile Health will partner with Living Goods to get smartphones to community health workers in six countries in Africa, bringing quality care to more than 34 million people.
- Subjects:
- Management of Health Care Services
- Keywords:
- Smartphones Public health personnel Community health services
- Resource Type:
- Video
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Video
What if we incentivized doctors to keep us healthy instead of paying them only when we're already sick? Matthias Müllenbeck explains how this radical shift from a sick care system to a true health care system could save us from unnecessary costs and risky procedures -- and keep us healthier for longer.
- Subjects:
- Management of Health Care Services and Public Health
- Keywords:
- Medical care Medical economics Medical care Cost of
- Resource Type:
- Video
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Video
The US health care system assumes many things about patients: that they can take off from work in the middle of the day, speak English, have a working telephone and a steady supply of food. Because of that, it's failing many of those who are most in need, says Mitchell Katz, CEO of the largest public health care system in the US. In this eye-opening talk, he shares stories of the challenges low-income patients face -- and how we can build a better system for all.
- Subjects:
- Management of Health Care Services and Health Sciences
- Keywords:
- Medical care Poor -- Health hygiene
- Resource Type:
- Video
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Video
There's no better way to stop a disease than to catch and treat it early, before symptoms occur. That's the whole point of medical screening techniques like radiography, MRIs and blood tests. But there's one medium with overlooked potential for medical analysis: your breath. Technologist Julian Burschka shares the latest in the science of breath analysis -- the screening of the volatile organic compounds in your exhaled breath -- and how it could be used as a powerful tool to detect, predict and ultimately prevent disease.
- Subjects:
- Health Sciences
- Keywords:
- Medicine Preventive Respiration
- Resource Type:
- Video
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Video
Drinking calcium-rich milk strengthens your bones -- but it's not the only thing you can do for a strong and healthy skeleton. Dr. Jen Gunter digs deep into the three layers of bone to explain why they weaken as we age and shares what you can do to maintain a healthy frame for years to come. Want to hear more from Dr. Gunter? Check out her podcast Body Stuff, from the TED Audio Collective.
- Subjects:
- Rehabilitation Sciences and Health Sciences
- Keywords:
- Bones -- Physiology
- Resource Type:
- Video