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Video
Dr. Bustamante begins his talk by explaining why one would wish to study biochemical reactions at the level of a single molecule. He explains that many processes within the cell are carried out by very few molecules. By studying single molecules, it is possible to obtain details about the mechanism of a reaction that cannot be ascertained by studying a population of molecules. Bustamante goes on to describe the technique of optical tweezers and how it can be used to manipulate single molecules. His lab has successfully used this method to follow DNA transcription one molecule at a time and RNA translation one codon at a time. In both cases, single molecule studies provided detailed information about complex biochemical processes.
- Subjects:
- Biochemistry
- Keywords:
- Biomolecules Molecular biology
- Resource Type:
- Video
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Video
This video series is designed to teach bench researchers how scientists develop and execute strategy. Content includes an overview of how scientific enterprises use business strategy such as determining value proposition, identifying stakeholders, and defining vision. Concepts will be reinforced using practical examples from academic and industry settings.
- Subjects:
- Management
- Keywords:
- Strategic planning
- Resource Type:
- Video
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Video
This video series is designed to teach bench researchers how scientists in scientific enterprises structure business deals to achieve strategic goals. Content covers an overview of the business development process and includes identifying gaps, deal types and structure, and defining success. Concepts will be reinforced using practical examples from academic and industry settings.
- Subjects:
- Management
- Keywords:
- Business planning Industrial management
- Resource Type:
- Video
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Video
The traditional way of taking a drug, such as a pill or injection, often results in plasma drug levels that cycle between too high and too low. To better maintain drug levels in the effective range, scientists have developed a variety of systems to optimize drug release. In his first talk, Bob Langer gives an overview of many of these controlled drug release technologies, including polymer and pump systems. Langer begins Part 2 with the story of how he became interested in drug release technologies, which is also a story of the power of perseverance. As a post-doc with Judah Folkman, and after much trial and error, Langer developed a polymer system that provided a slow and constant release of an anti-angiogenesis factor. Initially, his results were met with skepticism, by both scientists and the patent office. Today, many, many companies have developed peptide delivery systems based on that original work. Langer also describes ongoing research in areas such as targeted drug delivery and externally controlled microchips designed for drug delivery. In Part 3, Langer focuses on the materials used in drug delivery and medical devices. Many of the original materials used in medicine were adapted from completely unrelated uses and often generated their own problems. Langer describes work by his lab and others to make polymers designed for specific medical uses. For instance, a porous polymer can be shaped into an ear or nose and act as a scaffold onto which a patient’s cells can be seeded to grow a new structure. Different polymers have been successfully used as scaffolds to grow new blood vessels or artificial skin for burn victims.
- Subjects:
- Health Technology and Informatics and Health Sciences
- Keywords:
- Drugs -- Controlled release Controlled release technology
- Resource Type:
- Video
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Video
Synthetic biology can be used in industrial biotechnology to engineer metabolic pathways to create high-value chemicals using model microorganisms such as yeast. During the Synthetic Biology in Action course, participants engineered yeast to produce beta-caretone for industrial biotechnology purposes. In this talk, they describe the steps they took to engineer an existing yeast pathway to produce the new chemical. These steps include modeling the metabolic pathway outputs, DNA design, amplification, and assembly, and analysis of the final result.
- Subjects:
- Electronic and Information Engineering, Biochemistry, and Biology
- Keywords:
- Synthetic biology Biochemistry Yeast fungi -- Biotechnology
- Resource Type:
- Video
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Video
Inventor, entrepreneur and visionary Ray Kurzweil explains in abundant, grounded detail why, by the 2020s, we will have reverse-engineered the human brain and nanobots will be operating your consciousness.
- Subjects:
- Technology
- Keywords:
- Technological innovations Bioengineering Information Technology
- Resource Type:
- Video
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Video
Chris Anderson, then the editor of Wired, explores the four key stages of any viable technology: setting the right price, gaining market share, displacing an established technology and, finally, becoming ubiquitous.
- Subjects:
- Product Design and Mechanical Engineering
- Keywords:
- Product life cycle New products -- Development
- Resource Type:
- Video
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Video
At TEDIndia, Pranav Mistry demos several tools that help the physical world interact with the world of data -- including a deep look at his SixthSense device and a new, paradigm-shifting paper "laptop." In an onstage Q&A, Mistry says he'll open-source the software behind SixthSense, to open its possibilities to all.
- Subjects:
- Electronic and Information Engineering and Computing
- Keywords:
- Human-computer interaction Augmented reality
- Resource Type:
- Video
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Video
In this wide-ranging, thought-provoking talk, Kevin Kelly muses on what technology means in our lives -- from its impact at the personal level to its place in the cosmos.
- Subjects:
- Technology
- Keywords:
- Technology -- Social aspects Technological innovations -- Social aspects
- Resource Type:
- Video
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Video
Two-thirds of the world may not have access to the latest smartphone, but local electronic shops are adept at fixing older tech using low-cost parts. Vinay Venkatraman explains his work in "technology crafts," through which a mobile phone, a lunchbox and a flashlight can become a digital projector for a village school, or an alarm clock and a mouse can be melded into a medical device for local triage.
- Subjects:
- Technology
- Keywords:
- Digital divide Industries Primitive Technology -- Social aspects
- Resource Type:
- Video