PAIR Distinguished Lecture : Adhesion between Soft Materials and Tissues
During the lecture, Prof. Suo first explained the fundamental mechanics of hydrogels, illustrating how two brittle polymer networks — polyacrylamide and alginate — can be combined to form a highly tough and stretchable hybrid hydrogel. This “brittle + brittle = tough” design concept greatly enhances the material’s resistance to fracture through hysteresis and viscoelastic energy dissipation, increasing its fracture energy from approximately 10 J/m² to over 9,000 J/m². These advanced hydrogels also possess desirable properties such as stretchability, transparency and conductivity, enabling their use as ionic conductors in various biomimetic devices, including artificial muscles, stretchable electroluminescent devices and ionic transistors, thereby overcoming the fragility limitations of conventional biocompatible materials.
In the area of interface engineering, Prof. Suo further elaborated on how the synergistic interplay among chemistry, topology and mechanics enables robust tissue adhesion. He introduced pioneering techniques such as “topological adhesion” and “molecular staples”, which utilise biocompatible polymers to form instant, tough and non-covalent bonds on soft tissue surfaces. His research team has also successfully developed innovative materials, including “hydrogel paints” and photodegradable adhesives, which not only provide strong adhesive performance but can also be safely removed under ultraviolet (UV) light, offering breakthrough solutions for clinical applications such as surgical dressings and wound care.
The lecture also highlighted the translational applications of these materials in both biomedical and industrial fields. Prof. Suo introduced hydrogel-mesh composites designed for sutureless adhesive anastomosis in organ transplantation, a technology that can significantly reduce surgical trauma and the risk of fluid leakage. He further explained how the mechanical principle of multiscale stress deconcentration can increase the fatigue threshold of soft materials by tenfold. Beyond bioimplants, this concept has also been extended to the development of sustainable engineering materials, such as “green tyres” made from silica-filled natural rubber and highly durable natural rubber tanglemers.
Event date: 2/6/2026
Speaker: Prof. SUO Zhigang
Hosted by: PolyU Academy for Interdisciplinary Research
- 1:15:25


