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The lecture commenced with a warm welcome address by Prof. CHEN Qingyan, Director of PAIR, followed by a brief speaker introduction by Prof. WANG Zuankai, Associate Vice President (Research and Innovation) of PolyU. In his presentation, Prof. Yang highlighted that urgent need for tissue/organ biomanufacturing owing to the shortage of donation for organ transplantation. He pointed out some challenges in the in vitro manufacturing of tissues/organs, particularly in relation to accurate design, precise fabrication, and functional induction, which underscore the imperative need for new methods for tissue/organ manufacturing. Next, Prof. Yang outlined the development roadmap of biomanufacturing and shared specific examples demonstrating the research progress in 3D bioprinting. In concluding his presentation, Prof. Yang shared his insights on the future direction for biomanufacturing, as well as some significant accomplishments by him and his team at Zhejiang University in the field.
A question-and-answer session moderated by Prof. Wang was followed. Both the online and on-site audience had a fruitful discussion with Prof. Yang.
Even date: 2/1/2024
Speaker: Prof. Huayong Yang (Zhejiang University)
Moderator: Prof. Zuankai Wang (Hong Kong Polytechnic University)
Hosted by: PolyU Academy for Interdisciplinary Research
- Subjects:
- Biology and Biomedical Engineering
- Keywords:
- Tissue engineering Biomedical engineering Three-dimensional printing Regenerative medicine
- Resource Type:
- Video
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Video
Models arising in biology are often written in terms of Ordinary Differential Equations. The celebrated paper of Kermack-McKendrick (19271, founding mathematical epidemiology, showed the necessity to include parameters in order to describe the state of the individuals, as time elapsed after infection. During the 70s, many mathematical studies were developed when equations are structured by age, size, more generally a physiological trait. The renewal, growth-fragmentation are the more standard equations. The talk will present structured equations, show that a universal generalized relative entropy structure is available in the linear case, which imposes relaxation to a steady state under non-degeneracy conditions. In the nonlinear cases, it might be that periodic solutions occur, which can be interpreted in biological terms, e.g., as network activity in the neuroscience. When the equations are conservation laws, a variant of the Monge-Kantorovich distance (called Fortet-Mourier distance) also gives a general non-expansion property of solutions.
Event date: 19/1/2023
Speaker: Prof. Benoît Perthame (Sorbonne University)
Hosted by: Department of Applied Mathematics
- Subjects:
- Biology and Mathematics and Statistics
- Keywords:
- Biomathematics Equations
- Resource Type:
- Video
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Video
In this lesson, we'll be looking at the cell cycle. This is the lifespan of a eukaryotic somatic cell. A somatic cell is any cell in the body of an organism, except for sex cells such as sperm and egg cells. The cell cycle describes the sequence of cell growth and division. A cell spends most of its life a state called interphase. Interphase has three phases, the G1, S, and G2 phases. Interphase is followed by cell division, which has one phase, the M phase. Together these four phases make up the entire cell cycle. G1 of interphase is sometimes called growth 1 or gap phase 1. In G1, a cell is busy growing and carrying out whatever function it's supposed to do. Note that some cells, such as muscle and nerve cells, exit the cell cycle after G1 because they do not divide again. A cell enters the S phase after it grows to the point where it's no longer able to function well and needs to divide. The S stands for synthesis, which means to make, because a copy of DNA is being made during this phase. Once DNA replication is complete, the cell enters the shortest and the last part of interphase called G2, also known as growth 2 or gap phase 2. Right now, it's enough to know that further preparations for cell division take place in the G2 phase. Now that interphase is over, the cell is ready for cell division, which happens in the M phase. The M phase has two events. The main one is mitosis, which is division of the cell's nucleus, followed by cytokinesis, a division of the cytoplasm. So, at the end of M phase, you have two daughter cells identical to each other and identical to the original cell. Let's review. The cell cycle describes the life cycle of an individual cell. It has four phases, three in interphase and one for cell division. Most cell growth and function happen during G1. The cell enters the S phase when it needs to divide. In this phase the cell replicates its DNA. Replication just means the cell makes a copy of its DNA. In G2, the cell undergoes further preparations for cell division. Finally, we have cell division in the M phase. The M phase consists of mitosis, which is nuclear division, and cytokinesis, or division of the cytoplasm. We'll explore the details of mitosis and cytokinesis separately
- Subjects:
- Biology
- Keywords:
- Cell cycle
- Resource Type:
- Video
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Video
This mini-lecture gives an overview on how scientists have applied biotechnology techniques to develop medical treatment and food production through the manipulation of DNA. The Faculty of Applied Science and Textiles (FAST) and the Institute of Textiles & Clothing (ITC) organized the mini-lecture series for more than three years. The lectures aim to enrich students' knowledge in creative perspectives and arouse their interest in Sciences, Fashion and Textiles. In view of the unpredictable development of the COVID-19 pandemic, the upcoming mini-lecture Series will be switched from face-to-face mode to online mode.
- Subjects:
- Biology
- Keywords:
- Biotechnology Genetic engineering DNA
- Resource Type:
- Video
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Video
Synthetic biology can be used in industrial biotechnology to engineer metabolic pathways to create high-value chemicals using model microorganisms such as yeast. During the Synthetic Biology in Action course, participants engineered yeast to produce beta-caretone for industrial biotechnology purposes. In this talk, they describe the steps they took to engineer an existing yeast pathway to produce the new chemical. These steps include modeling the metabolic pathway outputs, DNA design, amplification, and assembly, and analysis of the final result.
- Subjects:
- Electronic and Information Engineering, Biochemistry, and Biology
- Keywords:
- Synthetic biology Biochemistry Yeast fungi -- Biotechnology
- Resource Type:
- Video
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Video
"We've been promised a future of chrome -- but what if the future is fleshy?" asks biological designer Christina Agapakis. In this awe-inspiring talk, Agapakis details her work in synthetic biology -- a multidisciplinary area of research that pokes holes in the line between what's natural and artificial -- and shares how breaking down the boundaries between science, society, nature and technology can lead us to imagine different possible futures.
- Subjects:
- Technology and Biology
- Keywords:
- Synthetic biology Sci9ence -- Social aspects
- Resource Type:
- Video
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Video
TED Fellow Lucy McRae is a body architect -- she imagines ways to merge biology and technology in our own bodies. In this visually stunning talk, she shows her work, from clothes that recreate the body's insides for a music video with pop-star Robyn, to a pill that, when swallowed, lets you sweat perfume.
- Subjects:
- Biomedical engineering and Biology
- Keywords:
- Synthetic biology Bioengineering
- Resource Type:
- Video
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Video
As we move through the world, we have an innate sense of how things feel -- the sensations they produce on our skin and how our bodies orient to them. Can technology leverage this? In this fun, fascinating TED-Ed lesson, learn about the field of haptics, and how it could change everything from the way we shop online to how dentists learn the telltale feel of a cavity.
- Subjects:
- Electronic and Information Engineering and Biology
- Keywords:
- Haptic devices Touch
- Resource Type:
- Video
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Video
Your mortal enemy has captured you and hooked you up to a bizarre experiment. He's extended your nervous system with one very long neuron to a target about 70 meters away. At some point, he's going to fire an arrow. If you can then think a thought to the target before the arrow hits it, he'll let you go. So who wins that race? Seena Mathew examines the speed of thought.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Neurons -- Physiology Thought thinking Brain -- Physiology
- Resource Type:
- Video
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Video
Resource inequality is one of our greatest challenges, but it's not unique to humans. Like us, mycorrhizal fungi that live in plant and tree roots strategically trade, steal and withhold resources, displaying remarkable parallels to humans in their capacity to be opportunistic (and sometimes ruthless) -- all in the absence of cognition. In a mind-blowing talk, evolutionary biologist Toby Kiers shares what fungi networks and relationships reveal about human economies, and what they can tell us about inequality.
- Subjects:
- Biology
- Keywords:
- Mycorrhizal fungi -- Ecology
- Resource Type:
- Video
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Video
Berg begins his lecture with a brief history of observations of bacterial motion. He then uses physics to describe the many hurdles that E. coli must overcome as it tries to swim up or down a chemical gradient. For instance, an entity as tiny as E. coli is constantly buffeted by Brownian motion and can neither stay still nor swim in a straight line. Then there is the question of how E. coli senses a gradient and translates that information into a change in its direction of movement. And finally, how does E. coli use its flagella to generate thrust at all? In Part 2, Berg explains that E. coli travels using a series of runs, when it moves in a straight line, and tumbles, when it changes direction. During a run, all of the flagella are moving counterclockwise in a tight bundle. During a tumble, one or more flagella switch to a clockwise movement and disengage from the bundle causing a change in the swimming direction. The motor that drives the rotation of the flagella is an amazing structure made of about 20 different protein parts. Berg tells us that chemosensory receptors on the cell surface detect a chemical gradient and transfer this information, via protein phosphorylation, to the motor. This chemical modification determines the direction of motor rotation and, hence, the direction the E. coli swims. An amazing system that E. coli has been perfecting for millions of years!
- Subjects:
- Physics and Biology
- Keywords:
- Bacteria -- Motility Physics Escherichia coli
- Resource Type:
- Video
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Video
In this screencast, learners examine the bones of the appendicular skeleton.
- Subjects:
- Health Sciences, Rehabilitation Science, and Biology
- Keywords:
- Human skeleton Human anatomy
- Resource Type:
- Video
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Video
Explore what proteins are, their structure, and their functions.
- Subjects:
- Medical Laboratory Science and Biology
- Keywords:
- Proteins -- Structure
- Resource Type:
- Video
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Video
In this learning activity you'll assemble the components of a prokaryotic cell and match the names and functions with each structure.
- Subjects:
- Biology
- Keywords:
- Prokaryote
- Resource Type:
- Video
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Video
In this screencast, learners examine the movement of fluid within the vascular system.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Capillaries Cardiovascular system
- Resource Type:
- Video
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Video
In this screencast, the learner identifies the kidney's internal and external structures.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Kidneys -- Anatomy Kidneys -- Physiology
- Resource Type:
- Video
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Video
In this screencast, we'll view the 10 major bones of the skull and read a description of each bone.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Head -- Anatomy Scalp
- Resource Type:
- Video
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Video
Students read about how acid/base balance affects a person's health. This activity includes animation.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Acid-base imbalances
- Resource Type:
- Video
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Video
In this screencast, learners examine the function and location of the motor neurons and the damage that can result when they are injured.
- Subjects:
- Health Sciences, Rehabilitation Science, and Biology
- Keywords:
- Motor neurons Brain -- Anatomy
- Resource Type:
- Video
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Video
In this video you'll study the structure of the cell membrane and construct it using the correct molecules.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Cell membranes
- Resource Type:
- Video
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Video
Learners conduct an experiment to illustrate how a greater number of particles in a "vessel" increases osmotic pressure.
- Subjects:
- Medical Laboratory Science and Biology
- Keywords:
- Cytology Osmoregulation
- Resource Type:
- Video
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Video
In this screencast, learners will match the muscle names to their corresponding locations in the human body.
- Subjects:
- Health Sciences, Rehabilation Sciences, and Biology
- Keywords:
- Human body Muscles
- Resource Type:
- Video
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Video
In this screencast, learners examine the steps of carbohydrate digestion.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Digestion Carbohydrates -- Metabolism
- Resource Type:
- Video
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Video
In this video, learners view the parts of an animal cell and its organelles.
- Subjects:
- Biology
- Keywords:
- Cell -- Physiology Cytology Cell organelles
- Resource Type:
- Video
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Video
Explore what passive transport diffusion is and how it moves water through a membrane.
- Subjects:
- Biology
- Keywords:
- Biological transport Cell -- Physiology
- Resource Type:
- Video
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Video
Learners view video clips demonstrating Gram's staining procedure. Correctly stained slides are shown.
- Subjects:
- Laboratory Techniques and Safety and Biology
- Keywords:
- Gram's stain
- Resource Type:
- Video
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Video
Bees have been rapidly and mysteriously disappearing from rural areas, with grave implications for agriculture. But bees seem to flourish in urban environments -- and cities need their help, too. Noah Wilson-Rich suggests that urban beekeeping might play a role in revitalizing both a city and a species.
- Subjects:
- Environmental Sciences and Biology
- Keywords:
- Honeybees
- Resource Type:
- Video
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Video
How do cancer cells grow? How does chemotherapy fight cancer (and cause negative side effects)? The answers lie in cell division. George Zaidan explains how rapid cell division is cancer's "strength" -- and also its weakness.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Cancer cells
- Resource Type:
- Video
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Video
Sue Desmond-Hellmann is using precision public health -- an approach that incorporates big data, consumer monitoring, gene sequencing and other innovative tools -- to solve the world's most difficult medical problems. It's already helped cut HIV transmission from mothers to babies by nearly half in sub-Saharan Africa, and now it's being used to address alarming infant mortality rates all over the world. The goal: to save lives by bringing the right interventions to the right populations at the right time.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Medicial informatics Big data Public health
- Resource Type:
- Video
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Video
Can we make tattoos both beautiful and functional? Nanotechnologist Carson Bruns shares his work creating high-tech tattoos that react to their environment -- like color-changing ink that can tell you when you're getting a sunburn -- and shows exciting ways they can deliver real-time information about our health.
- Subjects:
- Health Technology and Informatics and Biology
- Keywords:
- Tattooing -- Health aspects
- Resource Type:
- Video
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Video
Your lifelong health may have been decided the day you were born, says microbiome researcher Henna-Maria Uusitupa. In this fascinating talk, she shows how the gut microbes you acquire during birth and as an infant impact your health into adulthood -- and discusses new microbiome research that could help tackle problems like obesity and diabetes.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Microorganisms Medical genetics
- Resource Type:
- Video
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Video
What if we could use biology to restore our balance with nature without giving up modern creature comforts? Advocating for a new kind of environmentalism, scientist and entrepreneur Emily Leproust rethinks modern sustainability at the molecular level, using synthetic biology to create green alternatives. From lab-developed insulin and disease-resistant bananas to airplanes made of super-strong spider silk, she explains how reading and writing DNA can lead to groundbreaking innovations in health, food and materials.
- Subjects:
- Biology
- Keywords:
- Biotechnology Bioengineering
- Resource Type:
- Video
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Video
Easy access to nutrients has contributed to the increase in obesity in the human population. But, what is obesity and why isn’t everybody fat? Dr. Stephen O’Rahilly provides a biomedical perspective of obesity, and evaluates which genes could potentially shift the balance towards obesity. As he explains, one becomes obese when the balance between energy intake and energy spent is shifted. Surprisingly, mutations that lead to obesity in humans aren’t in genes involved in metabolism and energy storage, but failure in satiety signals in the brain that result in people eating too much. The excess of energy intake over energy expenditure leads to obesity. What is the consequence of obesity in human health? Physically, obesity can result in lower mobility and sleeping disorders. But, in humans, the link between obesity and metabolic diseases isn’t straightforward. For example, not everyone that’s obese becomes insulin resistant. As O’Rahilly explains, the probability of an obese individual to have a metabolic disease is linked to the capacity of adipose tissue to store the extra fat. Mutations that decrease fat storage in adipose tissue increase the chance of metabolic diseases, like insulin resistance, even when the person is not obese.
- Subjects:
- Health Sciences and Biology
- Keywords:
- Obesity -- Genetic aspects
- Resource Type:
- Video
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Video
We're going to take apart a plastic anatomy model and see what we can find in the abdomen. We'll identify as many organs as we can, see how they fit into the abdomen relative to one another, working our way from anterior to posterior.
- Course related:
- HTI17102 Imaging Anatomy
- Subjects:
- Health Sciences and Biology
- Keywords:
- Organs (Anatomy) Abdomen
- Resource Type:
- Video
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Video
In 40 episodes, Hank Green teaches you biology!
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Video
Masterpieces of microengineering, kinesins are motorized transport machines that move cellular materials to their correct locations in the cell so they can perform their functions. Kinesins have two feet, or "globular heads," that literally walk, one foot over another. Known as the "workhorses of the cell," kinesins can carry cargo many times their own size.
- Course related:
- ABCT2103 Cell Biology
- Subjects:
- Biology
- Keywords:
- Kinesin
- Resource Type:
- Video
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Video
We are two sisters on a mission to demystify science with humor and relevance by creating videos, GIFs, comics, and resources. Our content is focused on high school biology (Pinky is a former high school biology teacher), though we do receive comments that some of our content is useful for intro biology courses at the college level as well. We're for anyone wanting to learn biology! We frequently remind viewers that we cannot include all of the fascinating exceptions and details in a video under 10 minutes. We like to create memorable visuals to the content, but they're not scientific illustrations. Meaning, nitrogen and carbon don't tap dance. Our illustrated cell and molecule cartoons are definitely not to scale. DNA is usually a right-handed double helix (well...there are exceptions) and it doesn't have eyes...a face...or a top hat...
- Subjects:
- Health Sciences and Biology
- Keywords:
- Biology
- Resource Type:
- Video